Karen was born and raised in Edgewater Park, New Jersey. In 1985, she earned an Associate Degree in Accounting and Computer Programming from Taylor Business Institute in Mt. Laurel, New Jersey. Karen moved to the New Orleans area in 1994. Shortly after moving to Louisiana, she began her career in dentistry and joined Dr. Delcambre's team in 2000.
Karen and her husband, Frank, have three children, Chad, Craig, and Christopher. She enjoys watching her children play sports, going on vacations, and spending time with family and friends.